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Botanical drugs and supplements affecting the immune response

  • Thomas Brendler
    Thomas Brendler

    For the last 22 years, I have developed and managed projects for industry on the use of plants in medicine, food and cosmetics. As a consultant to the Millennium Challenge Corporation, the Centre for Development of Enterprise and the International Trade Centre I have been involved in the preparation, management and execution of various public funded research projects. In 2005 I co-founded the Association of African Medicinal Plants Standards. I currently serve as director of AAMPS and editor-in-chief of the AAMPS African Herbal Pharmacopoeia (2010). I have been author of Herb-CD®, a digital encyclopaedia of medicinal plants, and co-authored, edited and contributed to a wide range of publications on phytotherapy and natural product regulation, most notably “Physician’s Desk Reference for Herbal Medicines”, “Medicinal and Aromatic Plants of Indian Ocean Islands” and “A Practical Guide To Licensing Herbal Medicinal Products”.

    I am a member of the editorial board of Phytotherapy Research and a regular peer reviewer for Journal of Ethnopharmacology, Ethnobotany Research & Applications, Economic Botany and Herbalgram. I also contributed to the translation into English of the German Commission E monographs on medicinal plants. From 2009-2010 I spent one year as a visiting scholar at Rutgers University (NJ, USA), Department of Plant Biology and Pathology, Natural Product Research Group.

  • 1:12 reading time (ish)
  • Western herbal medicine Immunity

In times of health crisis, the potential benefit of botanical drugs and supplements emerges as a focus of attention.

This article was first published as a Research paper and by The American Botanical Council

Botanical drugs and supplements affecting the immune response

In times of health crisis, including the current COVID-19 pandemic, the potential benefit of botanical drugs and supplements emerges as a focus of attention, although controversial efficacy claims are rightly a concern. Phytotherapy has an established role in everyday self-care and health care, but, since botanical preparations contain many chemical constituents rather than single compounds, challenges arise in demonstrating efficacy and safety. However, there is ample traditional, empirical, and clinical evidence that botanicals can offer some protection and alleviation of disease symptoms as well as promoting general well-being. Newly emerging viral infections, specifically COVID-19, represent a unique challenge in their novelty and absence of established antiviral treatment or immunization. We discuss here the roles and limitations of phytotherapy in helping to prevent and address viral infections, especially regarding their effects on immune response.

Botanicals with a documented immunomodulatory, immunostimulatory, and antiinflammatory effects include adaptogens, Boswellia spp., Curcuma longa, Echinacea spp., Glycyrrhiza spp., medicinal fungi, Pelargonium sidoides, salicylate-yielding herbs, and Sambucus spp. We further provide a clinical perspective on applications and safety of these herbs in prevention, onset, progression, and convalescence from respiratory viral infections.

Read the full article here: https://onlinelibrary.wiley.com/doi/epdf/10.1002/ptr.7008

Thomas Brendler

For the last 22 years, I have developed and managed projects for industry on the use of plants in medicine, food and cosmetics. As a consultant to the Millennium Challenge Corporation, the Centre for... Read more

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